{"id":4388,"date":"2025-08-11T20:57:07","date_gmt":"2025-08-11T20:57:07","guid":{"rendered":"https:\/\/qelizaesthetics.com\/alcohol-consumption-and-overall-health-two-sides-of-the-same-coin\/"},"modified":"2025-08-11T20:57:07","modified_gmt":"2025-08-11T20:57:07","slug":"alcohol-consumption-and-overall-health-two-sides-of-the-same-coin","status":"publish","type":"post","link":"https:\/\/qelizaesthetics.com\/sq\/konsumi-i-alkoolit-dhe-shendeti-i-pergjithshem-dy-anet-e-se-njejtes-monedhe\/","title":{"rendered":"Konsumi i alkoolit dhe sh\u00ebndeti i p\u00ebrgjithsh\u00ebm: Dy an\u00ebt e s\u00eb nj\u00ebjt\u00ebs monedh\u00eb"},"content":{"rendered":"<p><span style=\"font-weight: 400;\">Alkooli konsumohet nga m\u00eb shum\u00eb se gjysma e popullsis\u00eb n\u00eb Amerik\u00eb dhe Evrop\u00eb, me rreth 2.3 miliard\u00eb njer\u00ebz q\u00eb jan\u00eb pijedash\u00ebs aktual\u00eb. N\u00eb vitin 2019, nj\u00eb n\u00eb dymb\u00ebdhjet\u00eb persona n\u00eb Bashkimin Evropian konsumonin alkool \u00e7do dit\u00eb. Globalisht, rreth 237 milion\u00eb burra dhe 46 milion\u00eb gra vuajn\u00eb nga \u00e7rregullime t\u00eb p\u00ebrdorimit t\u00eb alkoolit, me prevalenc\u00ebn m\u00eb t\u00eb lart\u00eb midis burrave dhe grave n\u00eb Evrop\u00eb (p\u00ebrkat\u00ebsisht 14.8% dhe 3.5%) dhe n\u00eb SHBA (p\u00ebrkat\u00ebsisht 11.5% dhe 5.1%). Po b\u00ebhet e qart\u00eb se konsumi i alkoolit \u00ebsht\u00eb nj\u00eb shqet\u00ebsim global me shtrirje sh\u00ebndet\u00ebsore, ekonomike dhe sociale. N\u00eb k\u00ebt\u00eb artikull, do t\u00eb preken tema t\u00eb tilla si metabolizmi i alkoolit, vlera ushqyese e alkoolit, si dhe pasojat sh\u00ebndet\u00ebsore t\u00eb konsumit t\u00eb tep\u00ebrt afatgjat\u00eb t\u00eb alkoolit. S\u00eb fundmi, do t\u00eb diskutohet nj\u00eb fenomen me r\u00ebnd\u00ebsi t\u00eb madhe i njohur si paradoksi i alkoolit.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Metabolizmi i alkoolit<\/strong><\/p>\n<p>Alkooli klasifikohet si drog\u00eb rekreative dhe \u00ebsht\u00eb nj\u00eb qet\u00ebsues i njohur i sistemit nervor. N\u00eb fakt, \u00ebsht\u00eb droga m\u00eb e p\u00ebrdorur gjer\u00ebsisht n\u00eb nivel global. Alkooli, i referuar ndonj\u00ebher\u00eb me emrin kimik etanol, \u00ebsht\u00eb nj\u00eb substanc\u00eb me veti q\u00eb shkaktojn\u00eb var\u00ebsi q\u00eb shkakton efektet karakteristike t\u00eb dehjes nga alkooli. Etanoli metabolizohet kryesisht n\u00eb stomak dhe m\u00ebl\u00e7i nga enzima alkool dehidrogjenaz\u00eb (ADH). ADH e shnd\u00ebrron alkoolin n\u00eb acetaldehid\u00eb, n\u00ebnprodukti toksik q\u00eb kontribuon n\u00eb var\u00ebsin\u00eb nga alkooli. Nd\u00ebr efektet e tjera, ai prodhon lumturi dhe eufori, ulje t\u00eb ankthit, rritje t\u00eb shoq\u00ebrueshm\u00ebris\u00eb, qet\u00ebsim, d\u00ebmtim t\u00eb indeve dhe d\u00ebmtim t\u00eb funksionit imunitar, njoh\u00ebs, t\u00eb kujtes\u00ebs, motorik dhe shqisor.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>P\u00ebrmbajtja ushqyese e alkoolit<\/strong><\/p>\n<p><span>Pijet alkoolike p\u00ebrb\u00ebhen kryesisht nga uji, etanoli dhe sasi t\u00eb ndryshme sheqeri. N\u00eb m\u00ebnyr\u00eb specifike, nj\u00eb pije standarde p\u00ebrmban 12 g alkool t\u00eb past\u00ebr. Kjo sasi gjendet n\u00eb 350 ml birr\u00eb (p\u00ebrmbajtje alkooli 5%), 220 ml pije alkoolike malti (p\u00ebrmbajtje alkooli 7%), 170 ml ver\u00eb (p\u00ebrmbajtje alkooli 12%) ose 450 ml pije alkoolike t\u00eb distiluara 80 grad\u00eb (p\u00ebrmbajtje alkooli 40%) (p.sh., xhin, rum, vodka, uiski). Kalorit\u00eb q\u00eb vijn\u00eb nga alkooli dhe sheqeri konsiderohen kalori boshe p\u00ebr shkak t\u00eb munges\u00ebs s\u00eb l\u00ebnd\u00ebve t\u00eb tjera ushqyese thelb\u00ebsore. Alkooli jo vet\u00ebm q\u00eb nuk p\u00ebrmban proteina, minerale dhe vitamina, por n\u00eb fakt pengon thithjen dhe p\u00ebrdorimin e l\u00ebnd\u00ebve ushqyese jet\u00ebsore si tiamina, vitamina B.<\/span><span>12<\/span><span>, acid folik dhe zink.&nbsp;<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Ndikimi i konsumit t\u00eb alkoolit n\u00eb parametrat sh\u00ebndet\u00ebsor\u00eb<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">Konsumi i shtuar i alkoolit, ve\u00e7an\u00ebrisht n\u00ebse \u00ebsht\u00eb kronik, shoq\u00ebrohet me rrezikun e zhvillimit t\u00eb nj\u00eb game t\u00eb gjer\u00eb problemesh sh\u00ebndet\u00ebsore, duke p\u00ebrfshir\u00eb \u00e7rregullime mendore dhe t\u00eb sjelljes, si\u00e7 \u00ebsht\u00eb var\u00ebsia nga alkooli, s\u00ebmundje t\u00eb m\u00ebdha jo-ngjit\u00ebse, si\u00e7 jan\u00eb cirroza e m\u00ebl\u00e7is\u00eb, kanceri, hipertensioni, kardiomiopatia, goditja n\u00eb tru dhe diabeti i tipit II, si dhe s\u00ebmundje infektive, si\u00e7 jan\u00eb pneumonia, tuberkulozi dhe HIV. N\u00eb m\u00ebnyr\u00eb specifike, p\u00ebrqindja e vdekjeve t\u00eb atribuueshme alkoolit tek burrat arrin n\u00eb 7.7% t\u00eb t\u00eb gjitha vdekjeve globale krahasuar me 2.6% t\u00eb t\u00eb gjitha vdekjeve tek grat\u00eb. P\u00ebr m\u00eb tep\u00ebr, konsumi i alkoolit gjat\u00eb shtatz\u00ebnis\u00eb mund t\u00eb shkaktoj\u00eb sindrom\u00ebn e alkoolit fetal dhe komplikime t\u00eb lindjes s\u00eb parakohshme. S\u00eb fundmi, por jo m\u00eb pak e r\u00ebnd\u00ebsishme, p\u00ebrdorimi afatgjat\u00eb i alkoolit zvog\u00eblon sintez\u00ebn e proteinave, duke ulur nd\u00ebrtimin e muskujve dhe q\u00ebndrueshm\u00ebrin\u00eb muskulore.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Nj\u00eb nga indet kryesore q\u00eb d\u00ebmton pirja e tep\u00ebrt e alkoolit \u00ebsht\u00eb m\u00ebl\u00e7ia, pasi abuzimi me alkoolin \u00ebsht\u00eb nj\u00eb shkak kryesor i morbiditetit dhe vdekshm\u00ebris\u00eb q\u00eb lidhet me m\u00ebl\u00e7in\u00eb. Spektri i s\u00ebmundjes alkoolike t\u00eb m\u00ebl\u00e7is\u00eb (SAL) varion nga steatoza e thjesht\u00eb deri te steatohepatiti alkoolik, fibroza progresive dhe cirroza. P\u00ebrgjigja m\u00eb e hershme dhe m\u00eb e zakonshme hepatike ndaj alkoolit \u00ebsht\u00eb akumulimi i tep\u00ebrt i yndyr\u00ebs (steatoza), pasi acetaldehida ushtron nj\u00eb s\u00ebr\u00eb efektesh n\u00eb rregullimin e lipideve hepatike q\u00eb nxisin steatoz\u00ebn. Sasia e alkoolit t\u00eb konsumuar \u00ebsht\u00eb shum\u00eb e lidhur me ashp\u00ebrsin\u00eb e SAL. Pirja e tep\u00ebrt e alkoolit gjithashtu mund t\u00eb shkaktoj\u00eb, n\u00eb nj\u00eb mas\u00eb m\u00eb t\u00eb vog\u00ebl, zhvillimin e pankreatitit dhe kancerit t\u00eb pankreasit.&nbsp;<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Jo vet\u00ebm ekspozimi kronik, por edhe ai akut ndaj alkoolit, q\u00eb arrin nivele t\u00eb larta t\u00eb dehjes nga alkooli, mund t\u00eb ndikoj\u00eb negativisht n\u00eb sh\u00ebndet, duke shkaktuar \u00e7rregullime hormonale, t\u00eb tilla si nivele t\u00eb larta t\u00eb kortizolit, t\u00eb cilat mund t\u00eb prishin aft\u00ebsin\u00eb e trupit p\u00ebr t\u00eb ruajtur homeostaz\u00ebn dhe p\u00ebr t\u00eb rregulluar n\u00eb m\u00ebnyr\u00eb efektive p\u00ebrgjigjen ndaj stresit. Ky \u00e7ekuilib\u00ebr p\u00ebrfundimisht mund t\u00eb rezultoj\u00eb n\u00eb \u00e7rregullime t\u00eb ndryshme dob\u00ebsuese, t\u00eb tilla si intoleranca ndaj stresit, dehidratimi, sh\u00ebrimi i reduktuar, nivelet e ul\u00ebta t\u00eb energjis\u00eb, funksioni njoh\u00ebs i d\u00ebmtuar, \u00e7rregullime imunitare dhe riprodhuese (cikle menstruale t\u00eb parregullta, menopauz\u00eb e hershme, nivele t\u00eb ul\u00ebta t\u00eb testosteronit), mosfunksionim i tiroides (TSH e reduktuar, T1).<\/span><span style=\"font-weight: 400;\">3,<\/span><span style=\"font-weight: 400;\"> dhe T<\/span><span style=\"font-weight: 400;\">4<\/span><span style=\"font-weight: 400;\"> ), etj.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">Efektet negative t\u00eb alkoolit n\u00eb sh\u00ebndet nuk jan\u00eb t\u00eb nj\u00ebjta p\u00ebr t\u00eb gjith\u00eb njer\u00ebzit; ato i atribuohen kryesisht ndryshimeve n\u00eb seks, ndryshueshm\u00ebris\u00eb nd\u00ebrindividuale (gjenetik\u00ebs), llojit t\u00eb pijeve alkoolike t\u00eb konsumuara (t\u00eb fermentuara ose t\u00eb distiluara), sasis\u00eb (t\u00eb ul\u00ebt, t\u00eb moderuar, t\u00eb lart\u00eb), koh\u00ebzgjatjes (akute, kronike), modeleve t\u00eb marrjes (\u00e7do dit\u00eb, me tepri, her\u00eb pas here), si dhe faktor\u00ebve socioekonomik\u00eb. P\u00ebr shembull, grat\u00eb paraqesin nj\u00eb ndjeshm\u00ebri m\u00eb t\u00eb madhe ndaj efekteve toksike t\u00eb alkoolit sesa burrat, duke treguar metaboliz\u00ebm t\u00eb ulur p\u00ebr t\u00eb nj\u00ebjt\u00ebn sasi alkooli.&nbsp;<\/span><\/p>\n<p><strong>Paradoksi i alkoolit<\/strong><\/p>\n<p>Paradoksi me alkoolin \u00ebsht\u00eb se, megjith\u00ebse konsumi i r\u00ebnd\u00eb kronik i alkoolit mund t\u00eb jet\u00eb i d\u00ebmsh\u00ebm p\u00ebr sh\u00ebndetin e p\u00ebrgjithsh\u00ebm, konsumi i moderuar i alkoolit duket se rrit p\u00ebrgjigjen imunitare dhe zvog\u00eblon rrezikun e zhvillimit t\u00eb diabetit t\u00eb tipit II dhe s\u00ebmundjeve kardiovaskulare. Konsumi i moderuar i alkoolit \u00ebsht\u00eb shoq\u00ebruar me nj\u00eb ulje t\u00eb sh\u00ebnuesve pro-inflamator\u00eb, si\u00e7 jan\u00eb CRP dhe IL-6, si dhe me rritje t\u00eb niveleve t\u00eb HDL-C, ndjeshm\u00ebri t\u00eb p\u00ebrmir\u00ebsuar ndaj insulin\u00ebs dhe homeostaz\u00eb t\u00eb glukoz\u00ebs. T\u00eb gjitha k\u00ebto jan\u00eb mekanizma t\u00eb mundsh\u00ebm q\u00eb mund t\u00eb shpjegojn\u00eb rrezikun m\u00eb t\u00eb ul\u00ebt t\u00eb zhvillimit t\u00eb \u00e7rregullimeve kardiometabolike te njer\u00ebzit q\u00eb konsumojn\u00eb alkool me mas\u00eb.<\/p>\n<p><span style=\"font-weight: 400;\">Cila \u00ebsht\u00eb frekuenca dhe\/ose sasia ditore\/javore e alkoolit q\u00eb b\u00ebn dallimin midis konsumit t\u00eb moderuar dhe t\u00eb r\u00ebnd\u00eb t\u00eb alkoolit dhe var\u00ebsis\u00eb nga alkooli?<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Pirja e tep\u00ebrt kronike p\u00ebrkufizohet si pirja e \u2265 60g alkool t\u00eb past\u00ebr p\u00ebr burrat dhe \u2265 40g p\u00ebr grat\u00eb, q\u00eb korrespondon me t\u00eb pakt\u00ebn 15 pije\/jav\u00eb p\u00ebr burrat dhe tet\u00eb pije\/jav\u00eb p\u00ebr grat\u00eb. Konsumi i moderuar i alkoolit p\u00ebrkufizohet si m\u00eb pak se 30g alkool n\u00eb dit\u00eb, q\u00eb korrespondon me dy pije standarde n\u00eb dit\u00eb p\u00ebr burrat dhe nj\u00eb pije standarde p\u00ebr grat\u00eb, ose deri n\u00eb 14 pije\/jav\u00eb p\u00ebr burrat dhe deri n\u00eb 7 pije\/jav\u00eb p\u00ebr grat\u00eb. Var\u00ebsia nga alkooli do t\u00eb thot\u00eb m\u00eb shum\u00eb se 25 pije\/jav\u00eb. Pijet alkoolike shpesh b\u00ebhen burimi kryesor i energjis\u00eb tek ata me \u00e7rregullim t\u00eb p\u00ebrdorimit t\u00eb alkoolit (AUD), duke \u00e7uar n\u00eb kequshqyerje. Individ\u00ebt me AUD shpesh kan\u00eb munges\u00eb t\u00eb nj\u00eb ose m\u00eb shum\u00eb l\u00ebnd\u00ebve ushqyese thelb\u00ebsore, duke p\u00ebrfshir\u00eb vitaminat A, C, D, E, folatin dhe tiamin\u00ebn. AUD shoq\u00ebrohet gjithashtu me inflamacion kronik, ulje t\u00eb libidos, infertilitet, atrofi gonadale, v\u00ebllim m\u00eb t\u00eb ul\u00ebt t\u00eb sperm\u00ebs, num\u00ebr dhe l\u00ebvizshm\u00ebri t\u00eb sperm\u00ebs, nivele t\u00eb ul\u00ebta t\u00eb testosteronit, cik\u00ebl menstrual t\u00eb parregullt dhe mosfunksionim t\u00eb tiroides. Individ\u00ebt e varur nga alkooli mund t\u00eb ken\u00eb gjithashtu mikrobiom\u00eb t\u00eb zorr\u00ebve t\u00eb d\u00ebmtuara dhe probleme serioze me gjumin.&nbsp;<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Si p\u00ebrmbledhje, megjith\u00ebse konsumi i alkoolit shoq\u00ebrohet kryesisht me pasoja negative sh\u00ebndet\u00ebsore, nj\u00eb konsum i moderuar i alkoolit duket se sjell rezultate pozitive sh\u00ebndet\u00ebsore, ve\u00e7an\u00ebrisht n\u00eb parametrat e sh\u00ebndetit kardiometabolik, si\u00e7 jan\u00eb ndjeshm\u00ebria ndaj insulin\u00ebs dhe nivelet e rritura t\u00eb kolesterolit t\u00eb mir\u00eb (HDL-C). Megjithat\u00eb, kjo nuk do t\u00eb thot\u00eb q\u00eb nj\u00eb individ q\u00eb nuk konsumon alkool duhet t\u00eb filloj\u00eb t\u00eb pij\u00eb p\u00ebr t\u00eb p\u00ebrfituar k\u00ebto p\u00ebrfitime, pasi ekzistojn\u00eb aspekte t\u00eb tjera t\u00eb stilit t\u00eb jetes\u00ebs, si\u00e7 jan\u00eb nj\u00eb diet\u00eb e sh\u00ebndetshme dhe ushtrimet e rregullta, t\u00eb cilat gjithashtu mund t\u00eb sh\u00ebrbejn\u00eb p\u00ebr p\u00ebrfitime t\u00eb tilla sh\u00ebndet\u00ebsore.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><em>&nbsp; &nbsp; &nbsp; Referencat<\/em><\/strong><\/p>\n<ol>\n<li><span style=\"font-weight: 400;\"> Barr T, Helms C, Grant K, Messaoudi I. Efektet e kund\u00ebrta t\u00eb alkoolit n\u00eb sistemin imunitar. Prog Neuropsychopharmacol Biol Psychiatry. 2016;65:242-251. DOI: <\/span><a href=\"https:\/\/doi.org\/10.1016%2Fj.pnpbp.2015.09.001\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">10.1016\/j.pnpbp.2015.09.001<\/span><\/a><\/li>\n<li><span style=\"font-weight: 400;\"> Jeon S, Carr R. Efektet e alkoolit n\u00eb metabolizmin e lipideve n\u00eb m\u00ebl\u00e7i. J Lipid Res. 2020;61(4):470-479. DOI: <\/span><a href=\"https:\/\/doi.org\/10.1194%2Fjlr.R119000547\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">10.1194\/jlr.R119000547<\/span><\/a><\/li>\n<li><span style=\"font-weight: 400;\"> Minzer S, Losno RA, Casas R. Efekti i alkoolit n\u00eb faktor\u00ebt e rrezikut kardiovaskular: A ka informacione t\u00eb reja? Ushqyesit. 2020;12(4):912. DOI: <\/span><a href=\"https:\/\/doi.org\/10.3390%2Fnu12040912\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">10.3390\/nu12040912<\/span><\/a><\/li>\n<li><span style=\"font-weight: 400;\"> Rachdaoui N, Sarkar DK. Patofiziologjia e efekteve t\u00eb abuzimit me alkoolin n\u00eb sistemin endokrin. Alcohol Res. 2017;38(2):255-276. DOI: <\/span><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/pmc5513689\/\" target=\"_blank\" rel=\"noopener\"><span style=\"font-weight: 400;\">PMC5513689<\/span><\/a><\/li>\n<li><span style=\"font-weight: 400;\"> Rehm J, Roerecke M. Efektet kardiovaskulare t\u00eb konsumit t\u00eb alkoolit. Trens Cardiovasc Med. 2017;27(8):534-538. DOI: <\/span><span style=\"font-weight: 400;\">10.1016\/j.tcm.2017.06.002<\/span><\/li>\n<li><span>Spear LP. Efektet e konsumit t\u00eb alkoolit tek adoleshent\u00ebt n\u00eb tru dhe sjellje. Nat Rev Neurosci. 2018;19(4):197-214. DOI: <\/span><a href=\"https:\/\/doi.org\/10.1038\/nrn.2018.10\" target=\"_blank\" rel=\"noopener\"><span>10.1038\/nrn.2018.10<\/span><\/a><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<div>\n<p style=\"text-align: right;\"><b>Jet\u00ebgjat\u00ebsia<\/b><\/p>\n<\/div>\n<hr>\n<p>&nbsp;<\/p><\/p>","protected":false},"excerpt":{"rendered":"<p>Alcohol is consumed by more than half of the population in America and Europe, with an estimated 2.3 billion people being current drinkers. In 2019, one in twelve people in the European Union consumed alcohol daily. Globally, an estimated 237 million men and 46 million women suffer from alcohol-use disorders, with the highest prevalence among [&hellip;]<\/p>","protected":false},"author":1,"featured_media":4406,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-4388","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/posts\/4388","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/comments?post=4388"}],"version-history":[{"count":0,"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/posts\/4388\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/media\/4406"}],"wp:attachment":[{"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/media?parent=4388"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/categories?post=4388"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/qelizaesthetics.com\/sq\/wp-json\/wp\/v2\/tags?post=4388"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}